The Science of Possibility

At Vertex, we invest in scientific innovation to create transformative medicines for people with serious diseases.

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An image of two scientists with one pointing at an image on a computer screen

Our Science

Investing in science

We’re focused on discovering, developing and producing innovative medicines so people with serious diseases can lead better lives.

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An image of a man sitting at a desk with two monitors

Careers

Help us transform lives

At Vertex, the world’s most talented and passionate people come together to advance science and transform lives.

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An image of two women sitting on Adirondack chairs outside with plants in the background.

What It's Like

Living with type 1 diabetes

We're on a journey to learn from some of our colleagues at Vertex about something they have in common: type 1 diabetes (T1D). Come along for the ride to see an unfiltered glimpse at what it's like to live with T1D — from traveling and exercising, to parenthood and health scares.

News

The FDA has accepted our Biologics License Application for our investigational treatment for IgA nephropathy

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We’ve been recognized by the National Kidney Foundation with the 2026 Kidney Biotech Innovation Award

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We’ve released our 2025 Corporate Responsibility Report, showcasing our commitment to operating responsibly and making a positive impact on patients, employees, communities and the environment

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We’ve received US FDA approval of a broader indication for our triple combination therapies, expanding availability to ~95% of all people with CF in the US

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We continue to make meaningful progress toward our goal of bringing transformative therapies to those living with cystic fibrosis thanks to the development of Fischer Rat Thyroid (FRT) cell assays in the research of rare CF mutations

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Working at Vertex

Our company is built on an inclusive culture that brings together the best and brightest in every field striving for one goal: to improve the lives of people with serious diseases.

Careers Students

Working at Vertex

Find a Vertex clinical trial

Volunteers who participate in clinical trials help make new medicines a reality.

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Featured stories

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Reflecting on a "hidden in plain sight" disease: Byron and Melissa’s IgAN story

Reflecting on a "hidden in plain sight" disease: Byron and Melissa’s IgAN story

3 min read

Discover Byron and Melissa's experience with lgA nephropathy (lgAN), the easy-to-overlook impact of the disease and the importance of early action and self-advocacy.

The Vertex Foundation: A reflection on 2025 and our work with the sickle cell disease community

The Vertex Foundation: A reflection on 2025 and our work with the sickle cell disease community

3 min read

The Vertex Foundation's Executive Director, Melodie Knowlton, reflects on 2025 achievements and ongoing support for the sickle cell disease community.

Inside Vertex: Guided by our values, delivering for patients

Inside Vertex: Guided by our values, delivering for patients

4 min read

Culture at Vertex has always been core to who we are, and that commitment matters even more as we scale. Chief Human Resources Officer Stephanie Franklin shares why she is passionate about amplifying our culture and values.

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